Association between autoimmune gastritis and gastric polyps: Clinical characteristics and risk factors

Table 5 Univariate and multivariate analysis of the characteristics most associated with the development of gastric polyps in patients with autoimmune gastritis

Variable	Univariate analysis (95%CI)	P value	Multivariate analysis (95%CI)	P value
Age	1.023 (1.007-1.038)	0.003	1.015 (0.998-1.033)	0.084
Sex
Male	1.057 (0.714-1.566)	0.781	1.019 (0.656-1.582)	0.933
Female
PCA
Positive	2.771 (1.629-4.716)	< 0.001	2.003 (1.130-3.549)	0.017
Negative
IFA
Positive	1.047 (0.685-1.599)	0.833	0.866 (0.538-1.394)	0.553
Negative
HP infection
Positive	0.749 (0.451-1.244)	0.265	0.897 (0.512-1.571)	0.704
Negative
Anemia
Yes	0.819 (0.561-1.196)	0.302	0.811 (0.533-1.233)	0.326
No
Gastrin-17	1.007 (1.004-1.010)	< 0.001	1.002 (0.998-1.005)	0.306
PG-I	0.992 (0.985-0.998)	0.008	0.992 (0.985-0.999)	0.031
PG-II	1.037 (1.001-1.074)	0.044	1.053 (1.010-1.097)	0.015
PG-I/PG-II	0.927 (0.884-0.971)	0.002
OLGA
0-II
III-IV	2.408 (1.648-3.519)	< 0.001	1.541 (0.963-2.464)	0.071
OLGIM
0-II
III-IV	1.927 (1.107-3.353)	0.020	0.954 (0.487-1.869)	0.891
ECL hyperplasia
Absent
Exist	0.225 (0.150-0.338)	< 0.001	3.116 (1.868-5.197)	< 0.001

PCA: Parietal cell antibodies; IFA: Intrinsic factor antibody; HP: Helicobacter pylori; PG: Pepsinogen; OLGA: Operative Link for Gastritis Assessment; OLGIM: Operative Link on Intestinal Metaplasia Assessment; ECL: Enterochromaffin-like; CI: Confidence interval.