Association between autoimmune gastritis and gastric polyps: Clinical characteristics and risk factors

Table 4 Pathological characteristics and distribution of gastric polyps

Pathology	Gastric polyp groups (n = 166, N = 4331)					P value
	HPs	Fundic polyps	gNET	Adenomas/LGD	Adenocarcinoma
Age (year), median (IQR)	59 (51-67)	56.5 (44.5-71.2)	63 (56-72)	67 (62.8-71.2)	67.5 (61.2-71)	0.012
Sex (female), n (%)	75 (68.8)	12 (66.7)	15 (88.2)	4 (66.7)	6 (37.5)	0.041
PCA positivity, n (%)	94 (86.2)	15 (83.3)	15 (88.2)	5 (83.3)	15 (93.8)	0.904
IFA positivity, n (%)	26 (23.9)	6 (33.3)	3 (17.6)	2 (33.3)	8 (50)	0.185
HP infection positivity, n (%)	10 (9.2)	4 (22.2)	1 (5.9)	0 (0)	9 (56.2)	< 0.001
PG-I (μg/L), median (IQR)	33.3 (25-42.8)	38.2 (24.5-48.3)	37.8 (24.1-57.2)	11.5 (11-19.8)	37 (25.8-43.9)	0.033
PG-II (μg/L), median (IQR)	8.8 (7.2-11)	9.3 (7.1-10.4)	9.3 (7.5-10.6)	7.8 (7.1-8.7)	8.1 (7-10.4)	0.919
PGI/II, median (IQR)	3.7 (2.5-4.9)	3.8 (2.1-5.1)	4.4 (2.7-5.2)	1.4 (1.2-1.9)	4.5 (3.3-6.2)	0.06
Gastrin-17 (pmol/L), median (IQR)	91 (69.2-136.4)	81.9 (35.2-117.7)	137.7 (113-176.9)	95 (75.7-109.2)	96.7 (59.1-137.1)	0.013
Vitamin B12 (pg/mL), median (IQR)	264 (154-352)	257.5 (140-361.8)	210 (82-320)	144 (102-301.5)	256.5 (98.5-360.8)	0.71
Anemia, n (%)	38 (34.9)	9 (50)	5 (29.4)	4 (66.7)	5 (31.2)	0.35

¹The total number of polyps.

HP: Helicobacter pylori; gNET: Gastric neuroendocrine tumor; LGD: Low-grade glandular dysplasia; IQR: Interquartile range; PCA: Parietal cell antibodies; IFA: Intrinsic factor antibody; PG: Pepsinogen.