Association between autoimmune gastritis and gastric polyps: Clinical characteristics and risk factors

Table 2 Differences between patients with and without polyps

Group, n (%)	Gastric polyp, 166 (31.3)	Non-gastric polyp, 364 (68.7)	P value
Age (year), median (IQR)	61 (52.25-69)	58 (47-66)	0.006
Sex, n (%)	112 (67.5)	250 (68.7)	0.859
PCA positivity, n (%)	147 (88.6)	268 (73.6)	< 0.001
IFA positivity, n (%)	42 (25.3)	89 (24.5)	0.833
HP infection positivity, n (%)	24 (14.5)	67 (18.4)	0.264
Anemia, n (%)	70 (42.17)	159 (43.68)	0.302
Iron deficiency anemia, n (%), mild/moderate/severe	52 (31.33), 44/8/0	111 (30.49), 91/14/6	0.406
Pernicious anemia, n (%), mild/moderate/severe	18 (10.84), 14/3/1	48 (13.19), 34/8/6	0.851
Gastrin-17 (pmol/L), median (IQR)	91.9 (34.2-138.9)	60.9 (12.6-98.4)	< 0.001
PG-I (μg/L), median (IQR)	34.83 (22.8-45.7)	30.0 (18.1-58.2)	0.51
PG-II (μg/L), median (IQR)	8.8 (7.2-10.9)	7.8 (6.2-11)	0.019
PG-I/PG-II, median (IQR)	3.7 (2.4-5.0)	3.7 (1.9-6.7)	0.464
Vitamin B12 (pg/mL), median (IQR)	256.0 (130.0-357.2)	238.0 (137.0-354.5)	0.994
Norm/low level, n (%)	107 (64.46)/59 (35.54)	224 (61.54)/140 (38.46)	0.584
OLGA (0/I /II/III/IV)	11/34/39/61/21	33/86/140/85/20	< 0.001
OLGIM (0/I/II/III/IV)	38/63/39/21/5	96/177/59/24/8	0.018
ECL hyperplasia (absent/linear/micronodular/macronodular)	86/29/25/9	301/33/21/9	< 0.001

IQR: Interquartile range; PCA: Parietal cell antibodies; IFA: Intrinsic factor antibody; HP: Helicobacter pylori; PG: Pepsinogen; OLGA: Operative Link for Gastritis Assessment; OLGIM: Operative Link on Intestinal Metaplasia Assessment; ECL: Enterochromaffin-like.