Prognostic value of PEA3 subfamily gene expression in cholangiocarcinoma

Figure 8 Inhibition of cholangiocarcinoma cell function after transfection with shRNA-PEA3 in vitro. A: PEA3 expression was considerably decreased in Rihoku bile duct epithelial (RBE) and human cholangiocarcinoma cells-9810 followed transfection with shRNA-PEA3; B: Statistics of the relative mRNA level; C: Transwell analysis showed the migration and invasion ability of RBE cells transfected with shRNA-PEA3; D: Statistics of the number of migrated cells; E: Statistics of the number of invading cells; F: Colony formation assay showing the proliferative capacity of RBE cells after transfection with shRNA-PEA3; G: Statistics of the number of colon cells. ^aP < 0.05. ^bP < 0.01. RBE: Rihoku bile duct epithelial; HCCC-9810: Human cholangiocarcinoma cells-9810.