Senegenin suppresses hepatocellular carcinoma by regulating O-GlcNAcylation

Figure 6 Mechanism of O-GlcNAcylation glycosylation effect on hepatocellular carcinoma cells. A: Western blot analysis of endoplasmic reticulum stress protein expression levels after O-linked N-acetylglucosamine transferase (OGT) overexpression; B: Dual luciferase assay was used to measure the activity of AP-1; C: OGT overexpression results in a Western blot analysis of the levels of NF-κB pathway protein expression. ER: Endoplasmic reticulum; OGT: O-linked N-acetylglucosamine transferase; JNK: C-Jun N-terminal kinase.