Senegenin suppresses hepatocellular carcinoma by regulating O-GlcNAcylation

Figure 5 Effect of senegenin regulating O-GlcNAcylation glycosylation on hepatocellular carcinoma cells. A: Senegenin's impact on O-GlcNAc glycosylation and O-linked N-acetylglucosamine transferase was discovered by Western blot in hepatoma cells; B: Using the cell counting kit-8 assay, the effect of senegenin-regulated O-GlcNAc glycosylation on the proliferating of hepatocellular carcinoma cells was evaluated; C: O-GlcNAc glycosylation regulated by senegenin on colony-forming ability of hepatoma cells; D: The effect of senegenin-regulated O-GlcNAc glycosylation on the capacity of hepatocellular carcinoma cells to migrate was examined using the transwell assay.