Senegenin suppresses hepatocellular carcinoma by regulating O-GlcNAcylation

Figure 2 Effects of O-GlcNAcylation and glycosylation on hepatocellular carcinoma cell proliferation and migrating. A: The impact of O-GlcNAcase inhibitors (TMG, PUG) on O-GlcNAcylation glycosylation in cells of BEL-7402 was determined using a western blot; B: The cell counting kit-8 assay was utilized to identify hepatocellular carcinoma (HCC) cell proliferating; C: Colony-forming ability of HCC cells; D: To track the migrating of liver cancer cells, the transwell assay was utilized. HCC: Hepatocellular carcinoma; OGT: O-linked N-acetylglucosamine transferase; DMSO: Dimethyl sulfoxide.