Inflammation-related markers and prognosis of alpha-fetoprotein producing gastric cancer

Figure 3 Kaplan-Meier survival curves for alpha-fetoprotein+ patients with different levels of inflammation-related peripheral blood markers. The cut-off values of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI) and prognostic nutritional index (PNI) were 270, 156.31, 0.46, 755.75, 1.36 and 42.18, respectively. NLR < 2.70 (n = 19); NLR ≥ 2.70 (n = 56); Log-Rank: P < 0.001; PLR < 156.31 (n = 21); PLR ≥ 156.31 (n = 54); Log-Rank: P = 0.001; MLR < 0.46 (n = 52); MLR ≥ 0.46 (n = 23); Log-Rank: P < 0.001; SII < 755.75 (n = 29); SII ≥ 755.75 (n = 46); Log-Rank P < 0.001; SIRI < 1.36 (n = 28); SIRI ≥ 1.36 (n = 47); Log-Rank: P = 0.001; PNI < 42.18 (n = 46); PLR ≥ 42.18 (n = 29); Log-Rank P < 0.001. AFP: Alpha-fetoprotein; GC: Gastric cancer; PNI: Prognostic nutritional index; ROC: Receiver operating characteristic; SII: Systemic immune-inflammation index; SIRI: Systemic inflammation response index.