Erythropoietin-induced hepatocyte receptor A2 regulates effect of pyroptosis on gastrointestinal colorectal cancer occurrence and metastasis resistance

doi:10.4251/wjgo.v16.i9.3781

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Sep 15, 2024 (publication date) through Jan 11, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Sep 15, 2024; 16(9): 3781-3797
Published online Sep 15, 2024. doi: 10.4251/wjgo.v16.i9.3781

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Figure 7 Erythropoietin-induced hepatocyte receptor A2 signaling in colorectal cancer cell invasion and metastasis. Created by the BioRender. EphA2: Erythropoietin-induced hepatocyte receptor A2; IL: Interleukin; STAT6: Signal transducer and activator of transcription 6; ERK1/2: Extracellular signal-regulated kinase 1/2; PI3K: Phosphoinositide 3-kinase; AKT: Protein kinase B; mTOR: Mechanistic target of rapamycin; AP1: Activator protein 1; MMPs: Matrix metalloproteinases; JAK: Janus kinase; GAP: GTPase-activating protein.

Citation: Zhang YK, Shi R, Meng RY, Lin SL, Zheng M. Erythropoietin-induced hepatocyte receptor A2 regulates effect of pyroptosis on gastrointestinal colorectal cancer occurrence and metastasis resistance. World J Gastrointest Oncol 2024; 16(9): 3781-3797
URL: https://www.wjgnet.com/1948-5204/full/v16/i9/3781.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i9.3781