Clinical and Translational Research
Copyright ©The Author(s) 2024.
World J Gastrointest Oncol. Sep 15, 2024; 16(9): 3955-3979
Published online Sep 15, 2024. doi: 10.4251/wjgo.v16.i9.3955
Table 2 Temporal trends in burden of gastrointestinal cancers among working-age population in China 1990-2019
Measure of burdenGenderType of GI cancersAAPCP valueTrend 1
Trend 2
Trend 3
Trend 4
Trend 5
Trend 6
Years
APC
P value
Years
APC
P value
Years
APC
P value
Years
APC
P value
Years
APC
P value
Years
APC
P value
ASIROverallColon and rectum cancer3.00< 0.0011990-1996-0.020.8521996-20002.99< 0.0012000-20047.64< 0.0012014-20104.80< 0.0012010-20161.00< 0.0012016-20193.57< 0.001
Esophageal cancer-2.08< 0.0011990-1997-1.29< 0.0011997-20042.40< 0.0012004-2007-4.68< 0.0012007-2014-6.37< 0.0012014-2017-3.22< 0.0012017-20190.830.129
Gallbladder and biliary tract cancer0.330.1371990-1995-2.52< 0.0011995-1998-1.2750.2361998-20014.620.0012001-20147.719< 0.0012014-20071.450.1862007-2019-1.17< 0.001
Liver cancer-3.35< 0.0011990-19942.2< 0.0011994-1998-2.12< 0.0011998-2001-6.75< 0.0012001-2005-17.96< 0.0012005-2010-2.16< 0.0012010-20191.36< 0.001
Pancreatic cancer1.43< 0.0011990-1995-0.73< 0.0011995-19981.480.061998-20043.48< 0.0012004-20111.78< 0.0012011-2016-0.150.5122016-20192.85< 0.001
Stomach cancer-1.05< 0.0011990-1996-2.50< 0.0011996-1999-0.030.9671999-20044.00< 0.0012004-2010-2.44< 0.0012010-2016-3.34< 0.0012016-20190.110.756
All GI cancers-0.74< 0.0011990-1993-0.200.5581993-1998-1.11< 0.0011998-2002-0.150.6582002-2016-1.39< 0.0012016-20191.61< 0.001N/AN/AN/A
FemaleColon and rectum cancer1.77< 0.0011990-1996-0.310.0371996-20011.89< 0.0012001-20044.72< 0.0012014-20103.03< 0.0012010-20160.160.3992016-20193.67< 0.001
Esophageal cancer-3.63< 0.0011990-1998-1.36< 0.0011998-20042.40< 0.0012004-2008-8.67< 0.0012008-2013-10.57< 0.0012013-2016-6.15< 0.0012016-20190.170.81
Gallbladder and biliary tract cancer-0.260.1151990-1998-2.61< 0.0011998-20014.169< 0.0012001-20047.40< 0.0012004-20070.130.8882007-2014-2.31< 0.0012014-2019-0.810.001
Liver cancer-4.40< 0.0011990-19950.060.8261995-1998-3.900.0061998-2001-7.45< 0.0012001-2005-16.59< 0.0012005-2011-3.56< 0.0012011-2019-0.170.223
Pancreatic cancer0.96< 0.0011990-1995-0.050.8111995-19980.600.5151998-20022.27< 0.0012002-20071.230.0012007-2016-0.010.8922016-20193.83< 0.001
Stomach cancer-2.04< 0.0011990-1998-2.44< 0.0011998-20041.35< 0.0012004-2015-4.21< 0.0012015-2019-0.190.399N/AN/AN/AN/AN/AN/A
All GI cancers-1.29< 0.0011990-1993-0.890.0091993-1998-1.68< 0.0011998-2003-0.400.0492003-2013-2.54< 0.0012013-2016-1.510.0232016-20191.91< 0.001
MaleColon and rectum cancer3.82< 0.0011990-19960.170.1831996-20004.04< 0.0012000-200410.27< 0.0012014-20115.39< 0.0012011-20160.910.0022016-20193.86< 0.001
Esophageal cancer-1.56< 0.0011990-1997-1.12< 0.0011997-20042.67< 0.0012004-2007-3.35< 0.0012007-2014-5.28< 0.0012017-2017-3.13< 0.0012017-20190.80.211
Gallbladder and biliary tract cancer0.90< 0.0011990-1995-2.23< 0.0011995-1998-0.420.5961998-20015.48< 0.0012001-20057.18< 0.0012005-20100.640.0212010-2019-0.93< 0.001
Liver cancer-2.99< 0.0011990-19942.71< 0.0011994-1998-1.76< 0.0011998-2001-6.38< 0.0012001-2005-18.26< 0.0012005-2010-1.55< 0.0012010-20191.85< 0.001
Pancreatic cancer1.74< 0.0011990-1995-1.19< 0.0011995-19992.43< 0.0011999-20044.65< 0.0012004-20122.32< 0.0012011-2016-0.530.232016-20192.52< 0.001
Stomach cancer-0.60< 0.0011990-1996-2.39< 0.0011996-19990.430.5871999-20045.16< 0.0012004-2010-1.66< 0.0012010-2016-3.12< 0.0012016-2019-0.060.884
All GI cancers-0.45< 0.0011990-19920.510.451992-1998-0.78< 0.0011998-20010.120.8562001-2012-0.84< 0.0012012-2016-1.250.0022016-20191.56< 0.001
ASMROverallColon and rectum cancer0.52< 0.0011990-1997-1.22< 0.0011997-20001.710.0092000-20044.69< 0.0012004-20110.64< 0.0012011-2016-1.56< 0.0012016-20191.190.001
Esophageal cancer-2.49< 0.0011990-1998-1.26< 0.0011998-20042.43< 0.0012004-2007-5.55< 0.0012007-2014-6.80 < 0.0012014-2017-3.63< 0.0012017-20190.020.97
Gallbladder and biliary tract cancer-0.010.9511990-1995-2.73< 0.0011995-1998-1.600.1361998-20014.440.0012001-20147.45< 0.0012004-20070.930.3792007-2019-1.57< 0.001
Liver cancer-3.80 < 0.0011990-19961.11< 0.0011996-2000-4.43< 0.0012000-2004-18.45< 0.0012004-2007-5.810.0012007-2012-2.34< 0.0012012-20191.51< 0.001
Pancreatic cancer1.38< 0.0011990-1995-0.77< 0.0011995-19981.410.071998-20043.49< 0.0012004-20111.71< 0.0012011-2016-0.230.3252016-20192.76< 0.001
Stomach cancer-2.66< 0.0011990-1997-3.041997-20000.720.3182000-20042.92004-2015-5.16< 0.0012015-2019-2.91N/AN/AN/A
All GI cancers-2.23< 0.0011990-1993-0.630.011993-2000-1.46< 0.0012000-2004-2.79< 0.0012004-2014-3.66< 0.0012014-2017-1.480.0032017-2019-0.120.77
FemaleColon and rectum cancer-0.72< 0.0011990-1997-1.7< 0.0011997-20010.130.7122001-20041.670.0372004-2011-0.98< 0.0012011-2015-2.49< 0.0012015-20190.610.018
Esophageal cancer-4.72< 0.0011990-1998-2.23< 0.0011998-20041.530.0012004-2007-9.83< 0.0012007-2013-11.69< 0.0012013-2016-70.0012016-2019-1.320.122
Gallbladder and biliary tract cancer-0.65< 0.0011990-1998-3.00< 0.0011998-20013.930.0012001-20047.26< 0.0012004-2007-0.550.5452007-2014-2.77< 0.0012014-2019-1.17< 0.001
Liver cancer-4.74< 0.0011990-1996-0.310.0871996-2000-5.65< 0.0012000-2004-16.99< 0.0012004-2007-6.39< 0.0012007-2012-4.25< 0.0012012-20190.040.771
Pancreatic cancer0.91< 0.0011990-19970.010.9621997-20061.81< 0.0012006-2016-0.090.3812016-20193.75< 0.001N/AN/AN/AN/AN/AN/A
Stomach cancer-3.48< 0.0011990-1998-3.13< 0.0011998-20040.390.0112004-2014-6.42< 0.0012014-2019-2.58< 0.001N/AN/AN/AN/AN/AN/A
All GI cancers-2.93< 0.0011990-1993-1.390.0011993-2004-2.36< 0.0012004-2013-5.21< 0.0012013-2016-2.310.0032016-2019-0.250.455N/AN/AN/A
MaleColon and rectum cancer1.32< 0.0011990-1996-0.99< 0.0011996-19991.230.0361999-20046.53< 0.0012004-20111.66< 0.0012011-2016-1.25< 0.0012016-20191.150.001
Esophageal cancer-1.89< 0.0011990-1997-1.23< 0.0011997-20042.42< 0.0012004-2007-3.86< 0.0012007-2014-5.73< 0.0012014-2017-3.49< 0.0012017-20190.140.819
Gallbladder and biliary tract cancer0.61< 0.0011990-1995-2.31< 0.0011995-1998-0.600.4491998-20015.31< 0.0012001-20056.8< 0.0012005-20100.250.3252010-2019-1.33< 0.001
Liver cancer-3.47< 0.0011990-19961.66< 0.0011996-2000-4.57< 0.0012000-2005-17.1< 0.0012005-2012-1.84< 0.0012012-20191.92< 0.001N/AN/AN/A
Pancreatic cancer1.69< 0.0011990-1995-1.21< 0.0011995-19992.41< 0.0011999-20044.63< 0.0012004-20122.25< 0.0012012-2016-0.610.1642016-20192.43< 0.001
Stomach cancer-2.26< 0.0011990-1996-3.02< 0.0011996-1999-0.430.6521999-20043.6< 0.0012004-2008-4.01< 0.0012008-2015-4.97< 0.0012015-2019-3.02< 0.001
All GI cancers-1.92< 0.0011990-1993-0.340.4361993-2000-1.01< 0.0012000-2015-2.96< 0.0012015-2019-0.750.011N/AN/AN/AN/AN/AN/A
ASDROverallColon and rectum cancer0.59< 0.0011990-1997-0.99< 0.0011997-20001.710.0022000-20044.09< 0.0012004-20110.67< 0.0012011-2016-1.29< 0.0012016-20191.55< 0.001
Esophageal cancer-2.53< 0.0011990-1997-1.43< 0.0011997-20041.99< 0.0012004-2007-5.58< 0.0012007-2014-6.98< 0.0012014-2017-3.48< 0.0012017-20190.210.71
Gallbladder and biliary tract cancer-0.020.8951990-1998-2.23< 0.0011998-20014.58< 0.0012001-20046.58< 0.0012004-20070.980.1672007-2015-1.74< 0.0012015-2019-0.97< 0.001
Liver cancer-3.77< 0.0011990-19961.17< 0.0011996-2000-4.55< 0.0012000-2004-18.41< 0.0012004-2007-5.820.0012007-2012-2.31< 0.0012012-20191.6< 0.001
Pancreatic cancer1.37< 0.0011990-1995-0.720.0011995-19981.670.0441998-20043.27< 0.0012004-20111.63< 0.0012011-2016-0.170.4772016-20192.88< 0.001
Stomach cancer-2.61< 0.0011990-1997-2.89< 0.0011997-20000.890.152000-20042.51< 0.0012004-2015-5.17< 0.0012015-2019-2.56< 0.001N/AN/AN/A
All GI cancers-2.22< 0.0011990-1994-0.660.0021994-2000-1.46< 0.0012000-2005-3.33< 0.0012005-2013-3.70< 0.0012013-2016-1.970.0022016-2019-0.170.535
FemaleColon and rectum cancer-0.68< 0.0011990-1996-1.22< 0.0011996-2005-0.080.1082005-2011-0.98< 0.0012011-2015-2.21< 0.0012015-20190.78< 0.001N/AN/AN/A
Esophageal cancer-4.70< 0.0011990-1998-1.80< 0.0011998-20041.190.0012004-2007-10.13< 0.0012007-2013-11.76< 0.0012013-2016-6.92< 0.0012016-2019-1.20.081
Gallbladder and biliary tract cancer-0.73< 0.0011990-1998-2.59< 0.0011998-20013.49< 0.0012001-20045.87< 0.0012004-2007-0.740.3082007-2014-2.8< 0.0012014-2019-1.12< 0.001
Liver cancer-4.77< 0.0011990-19960.190.2141996-2000-5.50< 0.0012000-2004-17.77< 0.0012004-2007-6.54< 0.0012007-2012-4.27< 0.0012012-20190.030.83
Pancreatic cancer0.85< 0.0011990-19970.270.0421997-20011.910.0012001-20070.840.0012007-2016-0.110.282016-20193.73< 0.001N/AN/AN/A
Stomach cancer-3.44< 0.0011990-1997-2.79< 0.0011997-2004-0.59< 0.0012004-2014-6.31< 0.0012014-2019-2.41< 0.001N/AN/AN/AN/AN/AN/A
All GI cancers-2.91< 0.0011990-1994-1.31< 0.0011994-2000-1.92< 0.0012000-2004-3.77< 0.0012004-2013-5.03< 0.0012013-2016-2.180.0012016-2019-0.130.601
MaleColon and rectum cancer1.38< 0.0011990-1996-1.03< 0.0011996-19991.180.0531999-20046.46< 0.0012004-20111.64< 0.0012011-2016-0.99< 0.0012016-20191.59< 0.001
Esophageal cancer-1.93< 0.0011990-1997-1.18< 0.0011997-20042.45< 0.0012004-2007-4.15< 0.0012007-2014-5.95< 0.0012014-2017-3.34< 0.0012017-20190.350.572
Gallbladder and biliary tract cancer0.53< 0.0011990-1995-2.49< 0.0011995-1998-0.820.3041998-20014.94< 0.0012001-20047.62< 0.0012004-20081.660.0012008-2019-1.13< 0.001
Liver cancer-3.44< 0.0011990-19961.59< 0.0011996-2000-4.74< 0.0012000-2005-16.87< 0.0012005-2012-1.84< 0.0012012-20192.00< 0.001N/AN/AN/A
Pancreatic cancer1.71< 0.0011990-1995-1.25< 0.0011995-19992.47< 0.0011999-20044.66< 0.0012004-20122.17< 0.0012012-2016-0.49< 0.0012016-20192.63< 0.001
Stomach cancer-2.21< 0.0011990-1996-3.03< 0.0011996-1999-0.260.7511999-20043.67< 0.0012004-2008-4.17< 0.0012008-2015-4.99< 0.0012015-2019-2.66< 0.001
All GI cancers-1.91< 0.0011990-1993-0.150.6991993-2000-1.13< 0.0012000-2014-3.07< 0.0012004-2019-0.79< 0.001N/AN/AN/AN/AN/AN/A
GI: Gastrointestinal; AAPC: Average annual percent change; APC: Annual percent change; ASIR: Age-standardized incidence rate; ASMR: Age-standardized mortality rate; ASDR: Age-standardized disability-adjusted life-year rate; N/A: Not applicable.