Protein tyrosine phosphatase non-receptor II: A possible biomarker of poor prognosis and mediator of immune evasion in hepatocellular carcinoma

doi:10.4251/wjgo.v16.i9.3913

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Sep 15, 2024 (publication date) through Sep 9, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Sep 15, 2024; 16(9): 3913-3931
Published online Sep 15, 2024. doi: 10.4251/wjgo.v16.i9.3913

Table 4 Univariate analysis of clinicopathological factors and overall survival in 126 hepatocellular carcinoma patients

Characteristic	P value	HR	95%CI
Characteristic	P value	HR	Lower	Upper
Sex	0.940	0.977	0.532	1.792
Age	0.334	0.762	0.439	1.322
Hepatitis virus coinfection	0.838	1.585	0.441	1.942
Liver cirrhosis	0.018	1.802	1.109	2.930
AFP level	0.258	1.326	0.813	2.163
Tumor size	0.649	1.119	0.689	1.818
Degree of differentiation	0.967	0.992	0.683	1.441
PTPN2	0.018	1.942	1.123	3.359

PTPN2: Protein tyrosine phosphatase non-receptor 2; AFP: α-fetoprotein; HR: Hazard ratio; CI: Confidence interval.

Citation: Li HY, Jing YM, Shen X, Tang MY, Shen HH, Li XW, Wang ZS, Su F. Protein tyrosine phosphatase non-receptor II: A possible biomarker of poor prognosis and mediator of immune evasion in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(9): 3913-3931
URL: https://www.wjgnet.com/1948-5204/full/v16/i9/3913.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i9.3913