Curcumin for gastric cancer: Mechanism prediction via network pharmacology, docking, and in vitro experiments

doi:10.4251/wjgo.v16.i8.3635

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Aug 15, 2024 (publication date) through Mar 10, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3635-3650
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3635

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Figure 2 Compound–target network. The mutual network between curcumin (central orange node) and its intersection targets (peripheral orange nodes) included 32 nodes and 31 edges. ESR1: Estrogen receptor 1; EGFR: Epidermal growth factor receptor; CYP3A4: Cytochrome P450 family 3 subfamily A member 4; MAPK14: Mitogen-activated protein kinase 14; CYP1A2: Cytochrome P450 family 1 subfamily A member 2; CYP2B6: Cytochrome P450 family 2 subfamily B member 6.

Citation: Yang PH, Wei YN, Xiao BJ, Li SY, Li XL, Yang LJ, Pan HF, Chen GX. Curcumin for gastric cancer: Mechanism prediction via network pharmacology, docking, and in vitro experiments. World J Gastrointest Oncol 2024; 16(8): 3635-3650
URL: https://www.wjgnet.com/1948-5204/full/v16/i8/3635.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i8.3635