Effect of acacetin on inhibition of apoptosis in Helicobacter pylori-infected gastric epithelial cell line

Figure 3 Acacetin inhibits the decline in cell viability and lactate dehydrogenase release induced by Helicobacter pylori infection. A: Cells were pre-treated with specified concentrations of acacetin extract for 2 h, followed by stimulation with Helicobacter pylori (H. pylori) [multiplicity of infection (MOI) = 1:100] for 24 h; B: After pretreatment with specified concentrations of acacetin extract for 2 h and subsequent stimulation with H. pylori (MOI = 1:100) for 24 h, the amount of lactate dehydrogenase released into the cell culture supernatant was measured. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001 vs control group; ^eP < 0.05, ^fP < 0.01, ^gP < 0.001, ^hP < 0.0001 vs H. pylori group.