Dysbiosis promotes recurrence of adenomatous polyps in the distal colorectum

Figure 3 Differences in gut bacteria between the mucosa of patients with recurrent colorectal polyps of different pathologic types and the mucosa of controls. A: Bubble plots with different colors showing the affiliation of intestinal genera to the phylum, and the size of the bubbles showing the abundance of the genera; B: Heatmaps of the top 30 different intestinal genera in the control (Con), non-adenomatous polyps (Pol)-0.5, Pol-10, adenomatous polyps (Ade)-0.5, and Ade-10 groups. Colors in the heatmaps are used to depict specific general abundances in the four groups, with blue denoting low abundance and red denoting high abundance; C-F: Sankey diagrams. The Pol-0.5, Pol-10, Ade-0.5, and Ade-10 groups, respectively, are compared to the Con group (left). The Sankey diagrams of the taxonomic data vary with the branching widths of the genera (third row) and phylum (second row). Genera are categorized according to Gram-positive and negative bacteria (right). The color and width of the branches represent the flow of specific genera in different groups, in different phyla, and belonging to different Gram classifications. Ade: Adenomatous polyps; Pol: Non-adenomatous polyps; Con: Control.