Expression and significant roles of the long non-coding RNA CASC19/miR-491-5p/HMGA2 axis in the development of gastric cancer

Figure 8 The oncogenic mechanism of CASC19 to gastric cancer in vivo. A: The efficiency of lentivirus silencing CASC19 was verified by reverse transcription polymerase chain reaction (RT-PCR); B: The tumor growth rate of the CASC19 silencing lentivirus infection group was slower, and the tumor weight was significantly smaller than that of the negative control group; C: The hematoxylin and eosin staining of the tumor; D: Tumors were stained with TUNEL; E: The tumor was subjected to immunohistochemical staining; F: RT-PCR was performed on the tumor to examine the expression levels of CASC19, miR-491-5p, and HMGA2. ^bP < 0.05 was compared with the control group and P < 0.05 was considered statistically significant.