Expression and significant roles of the long non-coding RNA CASC19/miR-491-5p/HMGA2 axis in the development of gastric cancer

Figure 2 The effect of miR-491-5p in gastric cancer. A: The targeting relationship between CASC19 and miR-491-5p by dual luciferase reporter experiments; B: The expression of miR-491-5p after knock down of CASC19; C: The effect of miR-491-5p on the proliferation of gastric cancer cells by cell counting kit-8 assay; D and E: The consequence of apoptosis result by miR-491-5p mimics and miR-491-5p inhibitor; F: The change of apoptosis-related proteins by miR-491-5p mimics and miR-491-5p inhibitor through western blot experiment; G: The change of epithelial-mesenchymal transition proteins by miR-491-5p mimics and miR-491-5p inhibitor through western blot experiment. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.05 was compared with the control group respectively. P < 0.05 was considered statistically significant.