Targeting colorectal cancer with Herba Patriniae and Coix seed: Network pharmacology, molecular docking, and in vitro validation

doi:10.4251/wjgo.v16.i8.3539

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3539-3558
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3539

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Figure 3 Protein-protein interaction analysis of the intersection targets between Herba Patriniae-Coix seed and colorectal cancer. A: The protein-protein interaction (PPI) network between the Herba Patriniae-Coix seed and colorectal cancer intersection targets; B and C: The top 30 core targets identified through PPI network analysis; D: The impact map revealing the relationship between traditional Chinese medicine, core components, and core genes.

Citation: Wang CL, Yang BW, Wang XY, Chen X, Li WD, Zhai HY, Wu Y, Cui MY, Wu JH, Meng QH, Zhang N. Targeting colorectal cancer with Herba Patriniae and Coix seed: Network pharmacology, molecular docking, and in vitro validation. World J Gastrointest Oncol 2024; 16(8): 3539-3558
URL: https://www.wjgnet.com/1948-5204/full/v16/i8/3539.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i8.3539