Targeting colorectal cancer with Herba Patriniae and Coix seed: Network pharmacology, molecular docking, and in vitro validation

doi:10.4251/wjgo.v16.i8.3539

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Aug 15, 2024 (publication date) through Dec 21, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3539-3558
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3539

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Figure 1 Flow chart depicting the study methodology. Various databases were searched to obtain common targets of colorectal cancer (CRC) and Herba Patriniae-Coix seed. Possible targets and pathways for CRC were analyzed via network pharmacology and finally verified through in vitro experiments.

Citation: Wang CL, Yang BW, Wang XY, Chen X, Li WD, Zhai HY, Wu Y, Cui MY, Wu JH, Meng QH, Zhang N. Targeting colorectal cancer with Herba Patriniae and Coix seed: Network pharmacology, molecular docking, and in vitro validation. World J Gastrointest Oncol 2024; 16(8): 3539-3558
URL: https://www.wjgnet.com/1948-5204/full/v16/i8/3539.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i8.3539