Copyright
©The Author(s) 2024.
World J Gastrointest Oncol. Aug 15, 2024; 16(8): 3376-3381
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3376
Published online Aug 15, 2024. doi: 10.4251/wjgo.v16.i8.3376
Figure 1 Mutual relationship between long non-coding RNAs, autophagy, and chemoresistance.
A: Long non-coding RNAs (lncRNAs) can promote (blue line) or inhibit (orange line) autophagy and chemoresistance. Autophagy-related lncRNAs can positively or negatively influence drug resistance; B: LncRNAs function as competing endogenous RNAs by binding to specific microRNAs, leading to the activation of autophagy and ultimately enhancing resistance to 5-Fluorouracil, cisplatin, and oxaliplatin. lncRNA: Long non-coding RNAs; 5-FU: 5-Fluorouracil.
- Citation: Yu JM, Sun CQ, Xu HH, Jiang YL, Jiang XY, Ni SQ, Zhao TY, Liu LX. Navigating the labyrinth of long non-coding RNAs in colorectal cancer: From chemoresistance to autophagy. World J Gastrointest Oncol 2024; 16(8): 3376-3381
- URL: https://www.wjgnet.com/1948-5204/full/v16/i8/3376.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i8.3376