Current trends and hotspots of depressive disorders with colorectal cancer: A bibliometric and visual study

Table 5 Clusters of the top 100 keywords

Cluster	Keyword	Count	Rank	Cluster	Keyword	Count	Rank
1	Chemotherapy	72	13	4	Colonoscopy	38	33
1	Survival	66	17	4	Risk-factors	27	46
1	Expression	53	22	4	Adenomas	24	50
1	Therapy	35	35	4	Flat	23	54
1	Association	33	38	4	Screening	22	60
1	Metastasis	24	48	4	Resection	20	68
1	Apoptosis	22	56	4	Surveillance	20	69
1	Invasion	18	76	4	Lesions	19	73
1	Activation	17	81	4	Efficacy	16	92
1	Cancer patient	17	82	4	Guidelines	16	93
1	Oxaliplatin	17	83	4	Endoscopic mucosal resection	15	96
1	Proliferation	17	84	5	Quality-of-life	425	1
1	Prognosis	15	95	5	Anxiety	157	2
1	Epidemiology	14	99	5	Psychological distress	98	3
1	Mechanisms	13	102	5	Survivors	95	5
2	Prevalence	88	8	5	Health	92	6
2	Women	81	9	5	Care	62	19
2	Impact	72	14	5	Social support	54	21
2	Mortality	53	23	5	Surgery	44	28
2	Follow-up	35	36	5	Stress	37	34
2	Comorbidity	31	40	5	Adjustment	35	37
2	Disorders	24	49	5	Intervention	24	51
2	Mental health	23	53	5	Self-efficacy	24	52
2	Age	21	62	5	Of-life	23	55
2	Interventions	21	63	5	Randomized controlled-trial	22	61
2	Adults	19	70	5	Stoma	18	79
2	Burden	19	71	6	Validation	71	15
2	Quality	19	72	6	Population	52	24
3	Risk	90	7	6	Predictors	45	27
3	Fatigue	65	18	6	Questionnaire	39	31
3	Symptoms	61	20	6	Validity	28	45
3	Depressive symptoms	48	26	6	Functional assessment	26	47
3	Prostate cancer	38	32	6	Reliability	21	66
3	Meta-analysis	31	41	6	Health-related quality of life	19	74
3	Inflammation	29	43	6	Long-term survivors	19	75
3	Physical activity	29	44	6	Instrument	17	88
3	Breast cancer	22	57	6	Personality	14	100
3	Exercise	22	58	7	Hospital anxiety	97	4
3	Survivorship	22	59	7	Distress	81	10
3	Physical activity	21	64	7	Depression scale	42	29
3	Prevention	21	65	7	Communication	21	67
3	Cancer survivors	18	77	7	Nonpolyposis colorectal-cancer	17	89
3	Patient-reported outcomes	18	78	7	Genetic testing	16	94
3	Adjuvant chemotherapy	17	85	7	Experience	15	97
3	Older adult	17	86	7	Ovarian-cancer	14	101
3	Sleep	17	87	8	Oncology	68	16
3	Cancer survivorship	16	91	8	Scale	33	39
4	Diagnosis	79	11	8	Pain	30	42
4	Colon	50	25	8	Life	15	98
4	Management	39	30	9	Outcomes	75	12
4	Colonoscopy	38	33	9	Morbidity	18	80