Targeting colorectal cancer with Herba Patriniae and Coix seed: Network pharmacology, molecular docking, and in vitro validation

Table 1 Basic information of the 19 active ingredients in Herba Patriniae-Coix seed

Herb	Mol ID	Molecule name	Oral bioavailability (%)	Drug-likeness	Target amount
BJC1	MOL001676	Vilmorrianine C	33.96	0.22	59
BJC2	MOL001677	Asperglaucide	58.02	0.52	100
BJC3	MOL001678	Bolusanthol B	39.94	0.41	100
BJC4	MOL001689	Acacetin	34.97	0.24	100
BJC5	MOL002322	Isovitexin	31.29	0.72	3
BJC6	MOL001697	Sinoacutine	63.39	0.53	100
BJC7	MOL000358	Beta-sitosterol	36.91	0.75	44
BJC8	MOL000359	Sitosterol	36.91	0.75	44
BJC9	MOL000422	Kaempferol	41.88	0.24	3
BJC10	MOL000449	Stigmasterol	43.83	0.76	41
BJC11	MOL000006	Luteolin	36.16	0.25	100
BJC12	MOL000098	Quercetin	46.43	0.28	100
YYR1	MOL001323	Sitosterol alpha 1	43.28	0.78	60
YYR2	MOL001494	Mandenol	42.00	0.19	100
YYR3	MOL002882	[(2R)-2,3-dihydroxypropyl](Z)-octadec-9-enoate	34.13	0.30	41
YYR4	MOL000359	Sitosterol	36.91	0.75	44
YYR5	MOL000449	Stigmasterol	43.83	0.76	41
YYR6	MOL008121	2-Monoolein	34.23	0.29	52
YYR7	MOL000953	CLR	37.87	0.68	46