Endoscopic detection and diagnostic strategies for minute gastric cancer: A real-world observational study

Table 1 Clinicopathological characteristics of minute gastric cancers (patients and lesions)

Item	Value
Patients, n	184
Sex (male/female)	107/77
Age, range (median), yr	38-85 (59)
Lesions	191
Endoscopy (ME-NBI/WLE or WLE-NBI)	131/60
Size, range (median), mm	1.0-5.0 (4.0)
Location (upper/middle/lower)	12/22/157
JGCA classification1 (Tub1/Tub2/Sig/GA-FG/GA-FGM/OGA)	65/10/5/8/2/1
Nakamura classification (differentiated/undifferentiated)	186/5
Therapy (ESD/surgery)	179/12
Depth of invasion (mucosa/submucosa)	180/11
Multiple cancer (absent/synchronous/heterochronous)	135/40/16
Morphology change (protruding/flat/depressed)	95/28/68
Colour change (reddish/yellowish-red/no colour change/whitish)	65/55/45/25

¹GA-FG/GA-FGM/OGA were classified as rare subtypes of gastric adenocarcinoma according to the fifth edition of the World Health Organization. For statistical convenience, they were merged with the Japanese Gastric Cancer Association classification.

JGCA: Japanese Gastric Cancer Association; ESD: Endoscopic submucosal dissection; WLE: White light endoscopy; NBI: Narrow-band imaging; ME-NBI: Magnifying endoscopy with narrow-band imaging; Tub1: Well differentiated tubular adenocarcinoma; Tub2: Moderately differentiated tubular adenocarcinoma; Por1/2: Poorly differentiated adenocarcinoma; Sig: Signet ring cell carcinoma; GA-FG: Gastric adenocarcinoma of fundic gland type; GA-FGM: Gastric adenocarcinoma of fundic gland mucosa type; OGA: Oxyntic gland adenoma.