Canopy FGF signaling regulator 3 affects prognosis, immune infiltration, and PI3K/AKT pathway in colon adenocarcinoma

Figure 3 Immune correlation analysis. A: Differences in immune microenvironment-related indexes (stomal, immune, and ESTIMATE scores); B: Differences in immune cell infiltration; C: Correlations between canopy FGF signaling regulator 3 (CNPY3) expression and immune cell infiltration; D-H: Correlations between CNPY3 expression and activated CD8⁺ T cells (D), CD4⁺ T cells (E), regulatory T cells (F), M2 macrophages (G), and M0 macrophages (H); I-K: Correlations between CNPY3 expression and expression of immunostimulatory factors (I), immune inhibitors (J), and MHC molecules (K); L-O: Patient response to immune checkpoint inhibitors. ^aP < 0.05; ^bP < 0.01, ^cP < 0.001, NS: Not significant; CNPY3: Canopy FGF signaling regulator 3.