RBM5 suppresses proliferation, metastasis and glycolysis of colorectal cancer cells via stabilizing phosphatase and tensin homolog mRNA

Figure 4 RNA binding motif 5 regulates the phosphatase and tensin homolog/PI3K/AKT pathway in colorectal cancer cells. A-D: Protein levels of phosphatase and tensin homolog, phosphoinositide 3-kinase, phosphorylated-protein kinase B (p-AKT) and protein kinase B (AKT) were determined by Western blot in HCT116 and SW480 cells. ^cP < 0.001. RBM5: RNA binding motif 5; PTEN: Phosphatase and tensin homolog; PI3K: Phosphoinositide 3-kinase; p-AKT: Phosphorylated-protein kinase B.