Aldehyde dehydrogenase 2 family member repression promotes colorectal cancer progression by JNK/p38 MAPK pathways-mediated apoptosis and DNA damage

Figure 3 Aldehyde dehydrogenase 2 family member silencing promotes the apoptosis of colorectal cancer cells. A: Flow cytometric analysis of apoptosis of CL-40 and SK-CO-1 cells; B: Detection of apoptosis marker protein (Bax and Bcl-2) in shRNA aldehyde dehydrogenase 2 family member-cells co-treated with Alda-1; C: The cell viability in CL-40 and SK-CO-1 cells was measured by cell counting kit-8. Data are displayed as the mean ± SD. ^bP < 0.01, ^cP < 0.001. ALDH2: Aldehyde dehydrogenase 2 family member.