Multi-Omics analysis elucidates tumor microenvironment and intratumor microbes of angiogenesis subtypes in colon cancer

Figure 2 Expression landscape of angiogenesis-related genes in colon cancer. A: Heatmap (green: low expression level; brown: high expression level) of the angiogenesis-related genes (ARGs) between the nontumor (blue) and tumor samples (red); B: Differences in angiogenesis pathway single-sample gene set enrichment analysis score between normal and colon cancer (CC) tissues; C: Volcano plot of the differential ARGs; D: The expression of 8 differentially expressed angiogenesis-related genes between normal and CC tissues; E: Univariate Cox regression analysis of 36 angiogenesis-related genes and seven genes with P < 0.05; F: Mutation frequencies and types of ARGs; G: The location of copy number variation (CNV) alteration of 36 ARGs on 23 chromosomes; H: Chromosomal localization of ARGs with CNV. ARGs: Angiogenesis-related genes. ^cP < 0.001.