Yiqi Jiedu Huayu decoction inhibits precancerous lesions of chronic atrophic gastritis by inhibiting NLRP3 inflammasome-mediated pyroptosis

Figure 2 Yiqi Jiedu Huayu increased the secretion of gastric mucosal-related factors and reduced inflammatory factors secretion in chronic atrophic gastritis rats with precancerous lesion of gastric cancer. The gastric mucosal-related factors and inflammatory factors were measure before and after Yiqi Jiedu Huayu decoction treatment in the chronic atrophic gastritis rats with precancerous lesion of gastric cancer. A: Serum interleukin-6 level was determined by enzyme-linked immunosorbent assay (ELISA); B: Serum tumor necrosis factor-α level was determined by ELISA; C: Serum C-reactive protein level was determined by ELISA; D: Serum gastrin level was determined by ELISA; E: Serum pepsin level was determined by ELISA; F: Serum somatostatin was determined by ELISA; G: Serum prostaglandin E2 level was determined by ELISA. The measurement data were presented as mean ± SD. n = 10. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. YJHD: Yiqi Jiedu Huayu decoction; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-α; CRP: C-reactive protein.