Prognostic significance of exportin-5 in hepatocellular carcinoma

Figure 6 Knockdown of exportin-5 can inhibit cell invasion and migration in SNU-398 and SNU-449 cells. SNU-398 and SNU-449 cells were transfected with shRNA-NC or shRNA- exportin-5. A and E: Cell invasion of SNU-398 were detected by transwell assays; B and G: Cell invasion of SNU-449 were detected by transwell assays; C and F: Wound-healing assays of SNU-398 were performed to assess cell migration; D and H: Wound-healing assays of SNU-449 were performed to assess cell migration. Results were mean ± SD for three individual experiments. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. XPO5: Exportin-5; NC: Control group.