Integrated single-cell and bulk RNA sequencing revealed an epigenetic signature predicts prognosis and tumor microenvironment colorectal cancer heterogeneity

doi:10.4251/wjgo.v16.i7.3032

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Jul 15, 2024; 16(7): 3032-3054
Published online Jul 15, 2024. doi: 10.4251/wjgo.v16.i7.3032

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Figure 9 Drug response and the signature. A: Drugs with different predicted IC₅₀ values were identified and visualized with a heatmap; B: Detailed information was showed with vioplot; C: The drug response prediction was mostly contributed by NDN, PHF2, and MECP2 according to the correlation analyses.

Citation: Liu HX, Feng J, Jiang JJ, Shen WJ, Zheng Y, Liu G, Gao XY. Integrated single-cell and bulk RNA sequencing revealed an epigenetic signature predicts prognosis and tumor microenvironment colorectal cancer heterogeneity. World J Gastrointest Oncol 2024; 16(7): 3032-3054
URL: https://www.wjgnet.com/1948-5204/full/v16/i7/3032.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i7.3032