Integrated single-cell and bulk RNA sequencing revealed an epigenetic signature predicts prognosis and tumor microenvironment colorectal cancer heterogeneity

Figure 7 Single cell infiltration of the signature. A: The candidate genes were mainly expressed in ‘basal’ cells; B: After calculating risk scores of each sample, the normalized proportion of high/low-risk groups was visualized; C: A bar plot; D: Sankey diagram; E: The signature is significantly associated with several cell types according to the single cell sequencing data by dividing high and low-risk groups; F: The signature is significantly associated with several cell types according to the single cell sequencing data by Pearson correlation.