Integrated single-cell and bulk RNA sequencing revealed an epigenetic signature predicts prognosis and tumor microenvironment colorectal cancer heterogeneity

Figure 2 Signature performance in the TCGA dataset. A: Overall survival period of high-risk samples is significantly shorter compared to low-risk samples; B: Heatmap of candidate genes suggests that high-risk samples have high expression of certain genes; C: Progression-free survival of group samples is similar to the overall survival pattern; D: Five-year survival receiver operating characteristic curve of the model and other clinical indicators. AUC: Area under the curve.