Kombo knife combined with sorafenib in liver cancer treatment: Efficacy and safety under immune function influence

Table 1 Single-factor Cox regression analysis and least absolute shrinkage and selection operator analysis Cox analysis

Gene	Univariate Cox regression analysis				LASSO Cox, Coefficient
	HR	HR 0.95L	HR 0.95H	P value
ADGRE5	1.029	1.012	1.048	1.07E-03	3.15E-05
CHPF2	1.057	1.025	1.089	3.90E-04	9.24E-03
DNAJC1	1.037	1.021	1.053	3.19E-06	0.015
NDUFAF1	0.929	0.887	0.974	1.99E-03	-0.006
PARP12	1.061	1.018	1.105	4.74E-03	3.51E-03
PPIA	1.011	1.006	1.016	3.92E-05	2.94E-03
RAMP3	0.949	0.921	0.979	7.63E-04	-0.013
SLC29A3	1.132	1.070	1.198	1.86E-05	0.049
SLC44A1	1.113	1.052	1.177	1.99E-04	0.038
VSIG4	1.021	1.007	1.034	2.22E-03	3.10E-03

HR: Hazard ratio; L: Low; H: High; LASSO: Least absolute shrinkage and selection operator analysis; SLC29A3: Solute carrier family 29 member 3; PPIA: Peptidylprolyl isomerase A.