Adipocytes impact on gastric cancer progression: Prognostic insights and molecular features

Table 5 Univariate and multivariate analysis of prognostic factors for disease-free survival in the validation set

Parameter	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Age in yr		0.025
≤ 60	0.629 (0.443-0.893)	0.029	0.665 (0.468-0.945)	0.056
> 60
Sex		0.302
Male
Female	0.793 (0.547-1.148)	0.293
Adipose infiltration		< 0.001
High
Low	0.347 (0.243-0.494)	< 0.001	0.362 (0.254-0.517)	< 0.001
Perineural invasion		0.732
No
Yes	0.918 (0.605-1.392)	0.735
Vascular invasion		0.239
No
Yes	1.299 (0.908-1.857)	0.229
M stage		0.003
M0
M1	3.315 (1.868-5.883)	< 0.001	3.057 (1.719-5.436)	0.001
T stage		0.937
T1
T2	0.870 (0.580-1.305)	0.572
T3	0.897 (0.579-1.391)	0.684
T4	0.880 (0.270-2.869)	0.859
N stage		0.325
N0
N1	0.982 (0.562-1.715)	0.957
N2	1.030 (0.626-1.695)	0.922
N3	1.691 (1.081-2.645)	0.053

CI: Confidence interval; HR: Hazard ratio.