Adipocytes impact on gastric cancer progression: Prognostic insights and molecular features

Table 3 Univariate and multivariate analysis of prognostic factors for overall survival in the training set

Parameter	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Age in yr		0.006
≤ 60	0.675 (0.533- 0.854)	0.006	0.571 (0.446-0.731)	< 0.001
> 60
Sex		0.030
Male	1.396 (1.077-1.809)	0.034	1.305 (1.003-1.697)	0.096
Female
Adipose infiltration		0.009
High	1.854 (1.290-2.664)	0.005	2.143 (1.472-3.121)	< 0.001
Low
Perineural invasion		0.061
No
Yes	1.424 (1.055-1.922)	0.053
Vascular invasion		0.019
No
Yes	1.389 (1.103-1.749)	0.019	1.057 (0.829-1.349)	0.707
M stage		< 0.001
M0
M1	7.094 (4.528-11.114)	< 0.001	5.424 (3.392-8.675)	< 0.001
T stage		< 0.001
T1
T2	1.092 (0.297-4.008)	0.911	0.757 (0.203-2.817)	0.728
T3	3.025 (0.919-9.955)	0.127	1.783 (0.532-5.970)	0.432
T4	3.902 (1.210-12.583)	0.056	2.220 (0.675-7.302)	0.270
N stage		0.845
N0		< 0.001
N1	1.542 (1.057-2.251)	0.060	1.406 (0.956-2.066)	0.146
N2	3.012 (2.064-4.395)	< 0.001	2.230 (1.540-3.430)	< 0.001
N3	3.895 (2.400-6.321)	< 0.001	2.394 (1.438-3.987)	0.005

CI: Confidence interval; HR: Hazard ratio.