Comprehensive serum proteomics profiles and potential protein biomarkers for the early detection of advanced adenoma and colorectal cancer

Table 2 Functions of potential protein biomarkers

Biomarkers	Protein names	Uniprot ID	Biological process	Molecular function
DIAPH1	Protein diaphanous homolog 1	O60610	Actin cytoskeleton organization, cytoskeleton organization	Actin binding, RNA binding, signaling receptor binding
VASP	Vasodilator-stimulated phosphoprotein	P50552	Actin cytoskeleton organization	Actin binding, Cadherin binding
RAB11B	Ras-related protein Rab-11B	Q15907	Constitutive secretory pathway, endocytic recycling	Cadherin binding, GTP binding
LBP	Lipopolysaccharide-binding protein	P18428	Acute-phase response	Lipopeptide binding
SAR1A	GTP-binding protein SAR1a	Q9NR31	COPII-coated vesicle cargo loading	GTP binding, GTPase activity
TUBGCP5	Gamma-tubulin complex component 5	Q96RT8	Cytoplasmic microtubule organization	Gamma-tubulin binding, microtubule binding
DOK3	Docking protein 3	Q7L591	Ras protein signal transduction	-