Shi-pi-xiao-ji formula suppresses hepatocellular carcinoma by reducing cellular stiffness through upregulation of acetyl-coA acetyltransferase 1

Figure 3 Representative images and statistical results of wounding healing and transwell assays. A and B: Representative images and statistical results of the wounding healing assay in the vehicle, Shi-pi-xiao-ji (SPXJ)-serum, methyl-β-cyclodextrin (MβCD), and water-soluble cholesterol (Chol) groups of MHCCC97H cells; C and D: Representative images and statistical results of wounding healing assay in the vehicle, SPXJ-serum, MβCD, and Chol groups of HepG2 cells; E and F: Representative images and statistical results of the transwell assay in the vehicle, SPXJ-serum, MβCD, and Chol groups of hepatocellular carcinoma cells. The results are expressed as means ± SEM (n= 3). ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ns: P > 0.05. SPXJ: Shi-pi-xiao-ji; MβCD: Methyl-β-cyclodextrin; Chol: Water-soluble cholesterol.