Sm-like 5 knockdown inhibits proliferation and promotes apoptosis of colon cancer cells by upregulating p53, CDKN1A and TNFRSF10B

doi:10.4251/wjgo.v16.i6.2716

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2716-2726
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2716

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Figure 2 The expression level of Sm-like 5 decreased after knockdown. A: High expression of Sm-like 5 (LSM5) in 4 colon cancer cell lines confirmed by real-time quantitative polymerase chain reaction (RT-qPCR); B-E: LSM5 expression decreased significantly after knockdown, as confirmed by RT-qPCR (B and C) and Western blotting (D and E). LSM5: Sm-like 5.

Citation: Mo CJ, Deng XY, Ma RL, Zhu K, Shi L, Li K. Sm-like 5 knockdown inhibits proliferation and promotes apoptosis of colon cancer cells by upregulating p53, CDKN1A and TNFRSF10B. World J Gastrointest Oncol 2024; 16(6): 2716-2726
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2716.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2716