Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer

doi:10.4251/wjgo.v16.i6.2697

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Jun 15, 2024 (publication date) through Nov 26, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2697-2715
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2697

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Figure 7 Molecular docking model of the predicted targets and indole-3-acetaldehyde. A: Matrix metalloproteinase-9-indole-3-acetaldehyde (IAAD); B: Angiotensin converting enzyme-IAAD; C: Poly ADP-ribose polymerase-1-IAAD; D: Matrix metalloproteinase-2-IAAD; E: Myeloperoxidase-IAAD. PHE: Phenylalanine; SER: Serine; THR: Threonine; VAL: Valine; ALA: Alanine; TYR: Tyrosine; LEU: Leucine; ILE: Isoleucine; ARG: Arginine.

Citation: Dai Z, Deng KL, Wang XM, Yang DX, Tang CL, Zhou YP. Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer. World J Gastrointest Oncol 2024; 16(6): 2697-2715
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2697.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2697