Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer

doi:10.4251/wjgo.v16.i6.2697

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2697-2715
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2697

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Figure 3 Indole-3-acetaldehyde induces apoptosis in HCT116 cells. A-D: Apoptosis of colorectal cancer cells was observed by annexin V-fluorescein isothiocyanate/propidium iodide co-staining; E and F: The relative mRNA levels of downstream genes regulated by aryl hydrocarbon receptor were determined by real-time fluorescence quantitative polymerase chain reaction. ^bP < 0.01 vs control group. CYP1A1: Cytochrome P450 family 1 subfamily A member 1; CYP1B1: Cytochrome P450 family 1 subfamily B member 1.

Citation: Dai Z, Deng KL, Wang XM, Yang DX, Tang CL, Zhou YP. Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer. World J Gastrointest Oncol 2024; 16(6): 2697-2715
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2697.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2697