Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study

Figure 2 Forest plots of univariate Mendelian randomization analysis. A: Univariate Mendelian randomization analysis for genetically causal associations of socioeconomic traits with gastroesophageal reflux disease and Barrett’s esophagus risk; B: Forrest plot for causal associations of socioeconomic traits with gastroesophageal reflux diseases and Barrett’s esophagus risk based on inverse variance weighted multivariate Mendelian randomization; C: Mendelian randomization estimates of socioeconomic traits on modifiable risk factors; D: Mendelian randomization estimates of modifiable risk factors on Barrett’s esophagus and gastroesophageal reflux disease. 95%CI: 95% confidence interval; IVW: Inverse variance weighted; SNPs: Single nucleotide polymorphisms.