Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study

Figure 1 Overview of the Mendelian randomization rationale, design, and procedures. GSCAN: Genome-wide association study and Sequencing Consortium of Alcohol and Nicotine Use; GWAS: Genome-wide association study; IVW: Inverse variance weighted; LD: Linkage disequilibrium; MDD: Major depressive disorder; MR: Mendelian randomization; MRC-IEU: The Medical Research Council Integrative Epidemiology Unit; PGC: Psychiatric Genomics Consortium; SNP: Single nucleotide polymorphism; UVMR: Univariate Mendelian randomization.