Hepatocellular carcinoma: An analysis of the expression status of stress granules and their prognostic value

Figure 5 Gene Ontology analysis and Kyoto Encyclopedia of Genes and Genomes analysis of differentially expressed genes between high- and low-risk groups in The Cancer Genome Atlas-Liver Hepatocellular Carcinoma, GSE25097, and GSE36376 combined datasets. A: The circle diagram visualization Gene Ontology (GO) enrichment analysis outcomes among the high- and low-risk groups, the outer circle is GO terms, red dots indicate genes overexpressed genes, blue dots indicate under-expressed genes, quadrilateral colors indicate the z-score of GO terms, blue indicates the z-score is negative, and the corresponding GO terms would probably exhibit inhibition, and red indicates z-score is positive, and it is more probable for the activation of the term to take place in the corresponding GO terms; B: Dot plot of GO enrichment analysis for differentially expressed genes; C: The abscissa represents the gene ratio. The ordinate represents the pathway name, the node size indicates the genes enriched number included within the pathway, and the node color is indicative of the P value; D: Biological processes function enrichment chord diagram, node color represents gene expression level. Red indicates the gene overexpressed gene, and blue indicates the under-expressed gene; E: Cellular component function enrichment chord diagram, node color represents gene expression level. Red indicates the gene overexpressed gene, and blue indicates the under-expressed gene; F: Molecular function enrichment chord diagram, node color represents gene expression level. Red indicates the gene overexpressed gene, and blue indicates the under-expressed gene; G: Kyoto Encyclopedia of Genes and Genomes function enrichment chord diagram, node color represents gene expression level. Red indicates the gene overexpressed gene, and blue indicates the under-expressed gene. FC: Fold change.