Early monitoring values of oncogenic signalling molecules for hepatocellular carcinoma

doi:10.4251/wjgo.v16.i6.2350

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2350-2361
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2350

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Figure 3 Abnormal angiopoietin-2 expression during hepatocarcinogenesis[37-39,43]. Neovascularization is a fundamental process involved in a variety of pathological processes that sustain the progression of hepatocellular carcinoma. angiopoietin-2 (Ang-2) is a key driver of tumour angiogenesis, and abnormal Ang-2 during hepatocarcinogenesis in rats is closely related to hepatic hypoxia. Ang-2 could be used as an early index to monitor the malignant transformation of hepatocytes. EMT: Epithelial-mesenchymal transition; HRE: Hypoxia-responsive element; VEGF: Vascular endothelial growth factor; HCC: Hepatocellular carcinoma.

Citation: Yao M, Fang RF, Xie Q, Xu M, Sai WL, Yao DF. Early monitoring values of oncogenic signalling molecules for hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(6): 2350-2361
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2350.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2350