Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patients

doi:10.4251/wjgo.v16.i6.2673

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Jun 15, 2024 (publication date) through Jun 29, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2673-2682
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2673

Table 3 Comparison of mismatch repair immunohistochemistry and microsatellite instability testing, n (%)

Test results of MSI	MMR IHC normal (n = 2092)	MMR IHC abnormal (n = 179)
MSS	2079 (99.4)	6 (3.4)
MSI-L	5 (0.2)	2 (1.1)
MSI-H	8 (0.4)	171 (95.5)

MSI: Microsatellite instability; MSI-H: Microsatellite instability-high; MSI-L: Microsatellite instability-low; MSS: Microsatellite-stable; MMR: Mismatch repair; IHC: Immunohistochemistry.

Citation: Chen H, Jiang RY, Hua Z, Wang XW, Shi XL, Wang Y, Feng QQ, Luo J, Ning W, Shi YF, Zhang DK, Wang B, Jie JZ, Zhong DR. Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patients. World J Gastrointest Oncol 2024; 16(6): 2673-2682
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2673.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2673