Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study

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Jun 15, 2024 (publication date) through Jun 29, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical and Translational Research

World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2631-2645
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2631

Table 4 Multivariate separate-sample Mendelian randomization analysis of the effect of socioeconomic traits

Exposure	Outcome	OR (95%CI)	P value	Mediation effect
Age completed full time education	GERD	0.27 (0.23, 0.33)	6.410E-46	10.83%
Age completed full time education	BE	0.13 (0.08, 0.23)	2.140E-13	10.58%
Age completed full time education	BE	0.11 (0.07, 0.20)	2.900E-14	3.50%
Age completed full time education	BE	0.14 (0.08, 0.24)	1.290E-13	6.88%
Average total household income before tax	GERD	0.36 (0.30, 0.44)	3.240E-23	9.75%

BE: Barrett’s esophagus; 95%CI: 95% confidence interval; GERD: Gastroesophageal reflux disease; OR: Odds ratio.

Citation: Liu YX, Bin CL, Zhang L, Yang WT, An BP. Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study. World J Gastrointest Oncol 2024; 16(6): 2631-2645
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2631.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2631