Hepatocellular carcinoma: An analysis of the expression status of stress granules and their prognostic value

Table 3 Gene Ontology analysis results

Ontology	ID	Description	Gene ratio	Bg ratio	P value	adj P value
BP	GO:0006417	Regulation of translation	46/93	463/18800	3.06e-49	2.93e-46
BP	GO:1903311	Regulation of mRNA metabolic process	31/93	294/18800	3.99e-33	1.91e-30
BP	GO:0006401	RNA catabolic process	29/93	280/18800	1.06e-30	3.39e-28
BP	GO:0006402	mRNA catabolic process	27/93	233/18800	6.75e-30	1.62e-27
BP	GO:0017148	Negative regulation of translation	27/93	248/18800	3.81e-29	7.3e-27
CC	GO:0035770	Ribonucleoprotein granule	44/95	261/19594	9.7e-58	1.16e-55
CC	GO:0036464	Cytoplasmic ribonucleoprotein granule	40/95	243/19594	1.09e-51	6.51e-50
CC	GO:0010494	Cytoplasmic stress granule	23/95	79/19594	1.3e-35	5.21e-34
CC	GO:0000932	P-body	16/95	93/19594	6.99e-21	2.1e-19
CC	GO:0016281	Eukaryotic translation initiation factor 4F complex	7/95	11/19594	1.63e-14	3.92e-13
MF	GO:0008135	Translation factor activity, RNA binding	16/95	84/18410	3.24e-21	3.23e-19
MF	GO:0003743	Translation initiation factor activity	14/95	51/18410	3.87e-21	3.23e-19
MF	GO:0090079	Translation regulator activity, nucleic acid binding	17/95	108/18410	5.48e-21	3.23e-19
MF	GO:0045182	Translation regulator activity	24/95	406/18410	4.16e-19	1.84e-17
MF	GO:0003730	mRNA 3’-UTR binding	18/95	222/18410	7.11e-17	2.52e-15

GO: Gene Ontology; BP: Biological process; CC: Cellular component; MF: Molecular function; UTR: Untranslated region.