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©The Author(s) 2024.
World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2463-2475
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2463
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2463
Table 1 Baseline characteristics of the study population, n (%)
| HCC (n = 180) | Healthy (n = 100) | F/χ2/Z value | P value | |
| Demographics | ||||
| Age, yr, mean (SD), gender | 52.46 (9.18) | 49.79 (8.26) | 2.318 | 0.129 |
| Male | 165 (91.7) | 85 (85) | 2.987 | 0.084 |
| Female | 15 (8.3) | 15 (15) | ||
| LFTs | ||||
| AST (U/L), median (IQR) | 47 (33, 76.75) | 20 (16, 25) | -11.534 | < 0.001 |
| ALT (U/L), median (IQR) | 38 (26, 59.75) | 21 (18, 25.75) | -9.764 | < 0.001 |
| GGT (U/L), median (IQR) | 86 (45, 147) | 26 (20, 36) | -9.744 | < 0.001 |
| ALP (U/L), median (IQR) | 100.5 (67.25, 149) | 62 (53, 78) | -7.354 | < 0.001 |
| HCC biomarkers | ||||
| AFP (U/L) median (IQR) | 25 (7.49, 572.6) | 4 (3, 5) | -11.269 | < 0.001 |
| GP73 (ng/mL) median (IQR) | 147.5 (111, 217.5) | 54 (45, 73.75) | -11.775 | < 0.001 |
| DCP (ng/mL) median (IQR) | 10 (7, 513) | 6 (2.25, 8) | -8.172 | < 0.001 |
| CK18-M65 (U/L) median (IQR) | 802 (469.5, 1769) | 119 (94, 194.5) | -12.536 | < 0.001 |
| CK18-M30 (U/L) median (IQR) | 407.5 (219, 890.75) | 99 (80, 144) | -10.572 | < 0.001 |
- Citation: He L, Zhang C, Liu LL, Huang LP, Lu WJ, Zhang YY, Zou DY, Wang YF, Zhang Q, Yang XL. Development of a diagnostic nomogram for alpha-fetoprotein-negative hepatocellular carcinoma based on serological biomarkers. World J Gastrointest Oncol 2024; 16(6): 2463-2475
- URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2463.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2463