Predictive value of preoperative routine examination for the prognosis of patients with pT2N0M0 or pT3N0M0 colorectal cancer

Table 2 Univariate Cox regression analysis of disease-free survival

Variables	BE	SE	Wald	P value	HR (95%CI)
Male, (%)	0.179	0.276	0.420	0.517	1.196 (0.696-2.055)
Age, yr	-.005	0.012	0.169	0.681	0.995 (0.972-1.018)
BMI, kg/m2	0.026	0.041	0.413	0.520	1.027 (0.947-1.113)
Diabetes mellitus (%)	-0.284	0.468	0.369	0.544	0.753 (0.301-1.883)
Hypertension (%)	-0.133	0.257	0.269	0.604	0.875 (0.529-1.447)
Smoking history (%)	0.610	0.280	4.751	0.029	1.840 (1.063-3.185)
Alcohol intake history (%)	0.590	0.324	3.315	0.069	1.805 (0.956-3.407)
Family history of CRC (%)	0.435	0.518	0.705	0.401	1.545 (0.560-4.266)
NAFLD (%)	0.393	0.288	1.857	0.173	1.482 (0.842-2.608)
WBC, 109/L	-0.027	0.077	0.122	0.727	0.974 (0.837-1.132)
LY, 109/L	0.035	0.210	0.028	0.868	1.036 (0.686-1.564)
MO, 109/L	-0.164	0.841	0.038	0.846	0.849 (0.163-4.413)
NEUT, 109/L	-0.037	0.090	0.167	0.683	0.964 (0.808-1.150)
Hb, g/L	0.005	0.006	0.727	0.394	1.005 (0.993-1.017)
PLT, 109/L	-0.005	0.002	5.957	0.015	0.995 (0.991-0.999)
T-BIL, μmol/L	0.006	0.025	0.066	0.798	1.007 (0.958-1.058)
D-BIL, μmol/L	-0.010	0.086	0.013	0.908	0.990 (0.836-1.172)
TP, g/L	0.002	0.021	0.012	0.913	1.002 (0.961-1.045)
ALB, g/L	-0.014	0.030	0.216	0.642	0.986 (0.931-1.045)
GLB, g/L	0.018	0.029	0.389	0.533	1.018 (0.962-1.078)
ALT, U/L	-0.002	0.008	0.036	0.849	0.998 (0.983-1.015)
AST, U/L	-0.016	0.019	0.637	0.425	0.985 (0.948-1.023)
TBA, μmol/L	0.000	0.023	0.000	0.990	1.000 (0.956-1.047)
PA, mg/L	0.002	0.002	0.857	0.355	1.002 (0.998-1.006)
UREA, mmol/L	-0.001	0.088	0.000	0.990	0.999 (0.841-1.186)
FBG, mmol/L	0.119	0.072	2.742	0.098	1.126 (0.978-1.297)
Cr, μmol/L	0.002	0.008	0.072	0.789	1.002 (0.986-1.019)
UA, mmol/L	-0.392	1.119	0.123	0.726	0.675 (0.075-6.055)
HbA1c, %	0.017	0.156	0.011	0.915	1.017 (0.749-1.380)
CEA, ng/mL	0.004	0.004	1.067	0.302	1.004 (0.996-1.013)
CA19-9, U/mL	0.000	0.001	0.071	0.789	1.000 (0.998-1.001)
TC, mmol/L	0.144	0.179	0.648	0.421	1.155 (0.813-1.639)
TG, mmol/L	0.216	0.232	0.868	0.351	1.241 (0.788-1.955)
HDL-C, mmol/L	-0.054	0.501	0.012	0.914	0.948 (0.355-2.529)
LDL-C, mmol/L	0.142	0.223	0.405	0.525	1.152 (0.744-1.784)
Apo-A1, g/L	-0.788	0.803	0.964	0.326	0.455 (0.094-2.194)
Apo-B, g/L	0.707	1.075	0.432	0.511	2.027 (0.246-16.676)
LP-a, mg/dL	-0.001	0.012	0.005	0.944	0.999 (0.977-1.022)

CRC: Colorectal cancer; NAFLD: Nonalcoholic fatty liver disease; BMI: Body mass index; WBC: White blood cell; LY: Lymphocyte; MO: Monocyte; NEUT: Neutrophil; Hb: Hemoglobin; PLT: Blood platelet count; T-BIL: Total bilirubin; D-BIL: Direct bilirubin; TP: Total protein; ALB: Albumin; GLB: Globulin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBA: Total bile acid; PA: Prealbumin; UREA: Urea nitrogen; FBG: Fasting blood glucose; Cr: Creatinine; UA: Uric acid; HbA1c: Glycosylated hemoglobin A1c; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low density lipoprotein cholesterol; Apo-A1: Apolipoprotein A1; Apo-B: Apolipoprotein B; LP-a: Lipoprotein A; HR: Hazard ratio; CI: Confidence interval.