Predicting the prognosis of hepatic arterial infusion chemotherapy in hepatocellular carcinoma

doi:10.4251/wjgo.v16.i6.2380

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World Journal of Gastrointestinal Oncology

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World J Gastrointest Oncol. Jun 15, 2024; 16(6): 2380-2393
Published online Jun 15, 2024. doi: 10.4251/wjgo.v16.i6.2380

Table 1 Biomarkers for predicting hepatic artery infusion chemotherapy prognosis

Biomarker	PFS HR (95%CI)	OS HR (95%CI)	ORR HR (95%CI)	ORR (%)	Ref.
NLR	1.363 (1.008-1.843)	1.492 (1.106-2.012)	1.918 (1.092-3.369)	37.6	[31]
NLR	1.984 (1.111-3.545)			24.3	[39]
DCP	2.460 (1.434-4.220)	3.097 (1.728-5.551)		24.3	[39]
AFP DCP		2.17 (1.23-3.92)		51.9	[52]
AFP DCP		1.9 (1.06-3.42)		56.4	[52]
VEGF		2.42 (1.33-4.38)		35.2	[43]
Serum transferrin		1 (0.132-0.603)		46.9	[47]
IL-28B		1.720 (1.072-2.759)	2.620(1.124-6.107)	51.9	[73]

NLR: Neutrophil to lymphocyte ratio; DCP: Des-γ-carboxy prothrombin; AFP: Alpha-fetoprotein; VEGF: Vascular endothelial growth factor; IL-28B: Interleukin-28B; PFS: Progression-free survival; OS: Overall survival; ORR: objective response rate; CI: Confidence interval.

Citation: Wang QF, Li ZW, Zhou HF, Zhu KZ, Wang YJ, Wang YQ, Zhang YW. Predicting the prognosis of hepatic arterial infusion chemotherapy in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(6): 2380-2393
URL: https://www.wjgnet.com/1948-5204/full/v16/i6/2380.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i6.2380