Multidisciplinary comprehensive treatment of massive hepatocellular carcinoma with hemorrhage: A case report and review of literature

Figure 2 Surgery-related and pathological findings of the patient. A: Three months postsurgery, a whole-body bone scan indicated no obvious metastatic lesions; B: The tumor was excised during surgery; C: Photo of the incision 10 d postsurgery; D-F: Representative HE images of the tumor. The tumor tissue exhibited extensive necrosis and hemorrhage, with 5% viable tumor tissue, 80% necrotic tumor tissue, and 15% tumor stroma (fibrous tissue and inflammation). The immunohistochemical staining results were as follows: CKP (+), vimentin (-), HepPar-1 (+), GPC-3 (+), CK8/18 (+), CD68 (macrophage+), P53 (wild-type), and Ki-67 (index = 60%). (D: 10 × 10 HE; E: 20 × 10 HE; F: 40 × 10 HE).